Hypopigmentation and white scarring
Hypopigmentation is due to the sensitivity of melanocytes to oxidative strees caused by UV radiation or the wound healing process itself. Although anti-oxidants can be effective there is a balance between pro-oxidant and anti-oxidant that produces optimal even skin tone. Hypopigmentation can have many different causes and its resolution is usually accomplished by using as many different tactics simultaneously.
Tactics, products, proceedures and substrates positively influencing the correction of Hypopigmentation
Derma rolling .3 mm derma needle or roller daily
Nitic Oxide -reduces oxidative strees od melanocytes
Calcium gradient of startum corneum
Piper Nigrum extract piperine- kinase c inhibitor
PH lower ph less acidic -Extra cellular
UVA UVB radiation
selenium zinc, copper iron
promotion of tyrosine , p53, high protien foods
The white discoloration can also occur during ant-aging ablation processes of chemical peels, microdermabration and laser treatments. This condition can be prevented post-proceedure.
The therapuetic approaches and products can also be used to address vitiligo an auto immune desease eefecting 300 million people
The most serious and difficult conditions can be caused by outright destruction of melanocyt or worst the neural crest cells that generate them. This could occur from an ablation process that goes to deep, deep burns trauma or infections or with skin grafts.
1. Preventing hypopigmentation
In the early stages of wound healing the nitric oxide (NO) from active macrophages counteracts oxoidative strees.There are several approaches to help prevent this uneven skin tone.